Dela Cruz Study

The PaulieStrong Foundation Research Summary – Filemon Dela Cruz MD. My experiences in the laboratory and the clinic, caring for children with cancer, have served as the foundation for my goal to identify and develop effective therapies for pediatric sarcomas. We have entered a new era of medicine where we can utilize new techniques and…

Slotkin Study

Emily Slotkin, MD Over the past forty years, intensive combinations of chemotherapy, surgery, and radiation have helped to improve outcomes for those afflicted with rhabdomyosarcoma, but for patients with disease that has spread or does not respond well to these therapies, this aggressive cancer remains very difficult to treat. New methods to attack rhabdomyosarcoma are…

Role of ZFP57 in regulating Imprinted Genre Expression in Human Rhabdomyosarcoma.

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and young adults. Current therapy has long-term side effects and achieves cure in less than 40% of metastatic patients, a feature that has not changed over the past 40 years. The two main subtypes of RMS, Embryonal (ERMS: 70% of cases and more prevalent…